Malaria was treated with quinine in the past. Recently Chloroquine (a derivative of quinine) is used effectively especially against Plasmodium falciparum. But recently Plasmodium falciparum (the deadliest of all) developed resistance against chloroquine. Malaria can be easily prevented using good health-care infrastructure. So there may be no requirement of drugs in 1st World Countries. But in third world countries like India the disease is treated primarily through chemotherapy. So scientists are searching for new drugs and also want to explore the reason behind resistance development. Recently $ 1.5 million grant is sanctioned from National Institute of Health (NIH) USA for this purpose. So we may hope something interesting in the coming year.
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